Track Particle Distribution in Real Time with FBRM® C35
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Understand Your Granulation - FBRM® C35 enables formulators and engineers to monitor real-time changes in particle count and dimension during cohesive wet or dry particle processing. Inline measurement enables Quality by Design (QbD) throughout granulation development, granulation scale-up, and granulation manufacturing.
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Control Batch-to-Batch Repeatability - FBRM® trends enable users to identify and troubleshoot unexpected process changes. Therefore, FBRM can be used to minimize batch failures, improve yield, and troubleshoot scale-up or technology transfer.
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Identify Batch Endpoint - FBRM® allows users to identify a distribution corresponding to the ideal batch endpoint. FBRM®real-time distributions can then be tracked relative to this target distribution to ensure consistent downstream particle flow, tableting, and dissolution.
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Ensure Consistent Measurements - The innovative FBRM® C35 addresses applications where window fouling is a potential issue. The FBRM® C35 patent-pending scraper keeps the FBRM® probe window clean allowing the system to track agglomeration, compaction, and breakage, even in the most cohesive particle conditions.
Reduce Development Time
Particle dimension is a critical parameter in granulation. Formulators and engineers can reduce development with FBRM® while designing process conditions which provide uniform flow properties and tablet dissolution profiles.
Optimize Scale-Up
FBRM® real-time particle characterization can be used to optimize and control batch to batch repeatability upon scale-up from the lab to manufacturing.
After purchasing Lasentec in 2001, METTLER TOLEDO has become the world leader for inline particle/droplet size, shape, and count characterization.